Annals of the New York Academy of Sciences , 2012 Comprehensive review of T4's mechanisms in wound healing and tissue repair, synergistic with BPC-157
A 2023 randomized, phase 2 crossover trial by Hansen et al
Side Effects Upset stomach, nausea, vomiting, diarrhea, headache, muscle pain/weakness, swelling of hands/lower legs/feet, tingling skin, or body odor ("fishy" smell) may occur
Studies show thymosin beta-4 accelerates wound healing by increasing reepithelialization by 42% at 4 days and 61% at 7 days post-injury, with treated wounds also contracting at least 11% more than controls
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The preclinical studies have shown promising results in animal models, where NP-mediated delivery of BDNF has led to neuroprotective effects (182)