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Figure 1 GSTP Inhibits Nuclear-Cytoplasmic Translocation of HMGB1 and Release from Macrophages To investigate the effect of GSTP on release of HMGB1 from macrophages, we performed in vitro experiments on cultured primary cells and cell lines

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PE-22-28 doubling of BrdU-positive cells similarly reflects a cumulative process

IGF-1 binding to the cognate receptor, IGF-1R, triggers a signaling cascade leading to proliferative and anti-apoptotic events

It also defends against insults from foreign compounds at the cellular level and protects vulnerable neurons from oxidative stress