Mitochondrial engagement, including binding to voltage-dependent anion channels, can heighten oxidative stress in nonlesional tissues and contribute to organ dysfunction independent of lesion-directed ferroptosis (94, 95)
A review of the mechanism of action, metabolic profile and haemodynamic effects of sodium-glucose co-transporter-2 inhibitors
This revelation reveals exciting possibilities in the realm of drug discovery, as GST inhibitors and its prodrugs offer a feasible strategy in designing anticancer drugs with the primary purpose of reversing tumor resistance
Letters 40 , 139146 (1994)
GLP-1 related dry mouth often persists regardless of fluid intake because the underlying cause involves changes in saliva production or composition, not just total body hydration
Additionally, certain bacterial metabolites directly influence incretin hormone expression