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Germ free animals used were obtained from the University of North Carolina Gnotobiotic Facility, which is supported by P30-DK034987-25-28 and P40-RR018603-06-08
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Any product marketed as retatrutide through online or private channels should be treated with extreme caution
This strategy was based on previous structural data showing that position 5 of the FFAT core motif is located within a hydrophobic pocket in the MSP domain of VAP 41 , with previous studies indicating that introducing a negative charge in this position causes a steric hindrance which effectively disrupts FFAT motifVAP interaction 42
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