Overload of NADPH oxidase causes decreased pollution defense to free radicals generated by pollution or pathogens
24 25 However, fasting for longer isnt necessarily better
(PubMed) Bryan J, Calvaresi E, Hughes D
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Cardiovasc Res 36:276281 Masaki I, Yonemitsu Y, Yamashita A, Sata S, Tanii M, Komori K, Nakagawa K, Hou X, Nagai Y, Hasegawa M et al (2002) Angiogenic gene therapy for experimental critical limb ischemia: acceleration of limb loss by overexpression of vascular endothelial growth factor 165 but not of fibroblast growth factor-2
References Monnier M, Dudler L, Gchter R, Maier PF, Tobler HJ, Schoenenberger GA