Clogging increases the pressure differential between the intake and outflow sides, and this can cause the filters pleats to flatten out or the frame of the filter to buckle
And thats it
Although lorazepam injection is indicated only for intermittent use (see INDICATIONS AND USAGE and DOSAGE AND ADMINISTRATION), if used inappropriately more frequently than recommended, abrupt discontinuation or rapid dosage reduction or administration of flumazenil, a benzodiazepine antagonist, may precipitate acute withdrawal reactions, including seizures, which can be life-threatening
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However, it also has depressant effects, relaxing and reducing stress after its initial stimulating action