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doi: 10.1016/j.ijpharm.2013.05.015 433 MonteroSSeras-FranzosoJAndradeFMartinez-TrucharteFVilar-HernndezMQuesadaMet al

Second, to slow down the excretion out of the body and increase half-life in the blood, peptides can be fused with the Fc fragment of an antibody and protein scaffolds such as Staphylococcus A antigen (Affibody) or conjugated with polyethylene glycol and fatty acids to enables the peptides to bind to albumin