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Various factors influence TMAO blood levels, including diet, GI microbial composition, and liver enzyme activity
Pathologic bradyarrhythmia results in reduced cardiac output and hemodynamic instability causing syncope, dizziness, or dyspnea
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For females, GPx helps maintain ovarian function by balancing reactive oxygen species essential for ovulation but harmful in excess
Statin therapy is known to potentiate the effect of antihypertensive drugs [32, 33] through vasodilation, which is due to increased nitric oxide synthase activity [34], downregulation of angiotensin II-type 1 receptors [35], and endothelin-1 production [36]
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