doi:10.2147/CCID.S128339 Watanabe F, Hashizume E, Chan GP, Kamimura A
Binding of AngII to its AT1 receptor leads to the activation of MAP kinases, phosphorylation of tyrosine kinases and production of ROS, all of which induce VSMC proliferation
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In summary, our findings establish SLC25A39 as a pro-oncogenic factor in LUAD whose aberrant upregulation is linked to AFG3L2 downregulation
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