Decreased appetite Expected effect that contributes to weight loss
This cohort was a bit of a mixed bag
Clin Gastroenterol Hepatol 6(6):635643.e1 Szayna M, Doyle ME, Betkey JA, Holloway HW, Spencer RG, Greig NH et al (2000) Exendin-4 decelerates food intake, weight gain, and fat deposition in Zucker rats
Benefits: Enhanced fat burning (especially visceral fat) No effect on insulin or blood sugar No impact on IGF-1 Supports preservation of muscle during calorie deficit Dosing: 300-600mcg daily, subcutaneous Best on empty stomach in morning Timeline: Fat loss becomes noticeable 4-6 weeks Continued fat loss through 12+ weeks Best for: Fat loss without metabolic concerns
In March, her doctor prescribed Wegovy for weight loss
In conclusion, while tirzepatide may be effective for managing diabetes and weight, its use during pregnancy is not recommended due to the lack of clear evidence about its safety