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2017;10:1179064417695255 Sadhu SS, Wang S, Dachineni R, Averineni RK, Yang Y, Yin H, et al

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Sodium-glucose cotransporter-2 inhibitor luseogliflozin added to glucagon-like peptide 1 receptor agonist liraglutide improves glycemic control with bodyweight and fat mass reductions in Japanese patients with type 2 diabetes: a 52-week, open-label, single-arm study

When Wnt signaling is activated, -catenin accumulates in the cytoplasm and enters the nucleus, where it binds to T-cell factor (TCF)/lymphoid enhancer factor (LEF) transcription factors and promotes the expression of osteogenesis-related genes, thereby increasing bone formation (53)