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The emerging role of polyphenols in the management of type 2 diabetes
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Activation of FXR stabilizes the nuclear co-repressor (NcoR) at the NF-B response element on the IL-1 promoter, while decreasing the expression of TNF-, IL-1, IL-2, IL-6 and IFN- mRNA, thereby reducing the extent of inflammation (Vavassori et al., 2009)
The CCA for the remaining meta-analyses was 2%, indicating a slight level of overlap