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These include immune-mediated cytokine release, hormonal modulation through the hypothalamicpituitaryadrenal (HPA) axis, and neural pathways involving both the enteric nervous system (ENS) and the vagus nerve (Guzzetta et al., 2022
These findings deepen our understanding of the relationship between IGF-1 and tendon repair and provide a foundation for optimizing IGF-1 delivery strategies to enhance healing outcomes
Challenges and solutions: The care of these patients requires tertiary referral centers where Level IV neonatal intensive care unit (NICU) and Level I pediatric intensive care unit (PICU) with ECMO capabilities are available
749,750,751,752 Moreover, macrophages significantly influence liver aging, particularly through TGF- signaling
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