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However, severe, recurrent, or widespread bruising warrants medical review to exclude underlying clotting disorders

Among these, artesunate, sevoflurane, dihydroartemisinin, brusatol, nisin, hederagenin, glaucocalyxin A, nootkatone, cannabinoids and ophiopogonin B successfully promote ferroptosis in diverse cancer cell types mediated by the ER stress branch ATF4-CHOP-CHAC1 (Joo et al., 2012

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Fourth, well-designed human trials in a specific, measurable indication (rather than broad anti-aging framing) would be needed before any efficacy claim could be made