Animal studies show that DPP-4 inhibition does not improve glucose homeostasis in mice with genetic deletion of GLP-1 and GIP receptors, highlighting the critical role of GLP-1 in the mechanism of action of DPP-4 inhibitors (46)
J., Martaindale, M
Pregnancy testing should be performed when applicable, and patients who could become pregnant should be counseled on contraception during treatment
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