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Apart from epicanthal folds, additional midface/ocular signs were palpebral ptosis and sunken eyes (both 32%) and infraorbital creases (29.3%) (Fig

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2.3.3 Substance use within the family Exposure to substance use within the family was assessed using three items (1) binge drinking in the household (e.g., Does anyone in your household drink excessive alcohol or get drunk frequently? )

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