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Tepperman, Caldwell, and Tepperman 1964

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Common gastrointestinal side effects (nausea, bloating) may make rich or sweet foods less appealing during treatment

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Because tirzepatide activates two receptors (GLP-1 and GIP) while semaglutide activates one (GLP-1 only), the shape of this dose-response relationship may differ between the medications