In their paper on the study, published in JAMA Ophthalmology , the researchers noted that the substantially increased risk of NAION observed in patients on semaglutide appears not to be due to differences in baseline characteristics between the cohorts. They proposed the possibility that expression of the GLP-1 receptor in the human optic nerve and GLP-1 RA-induced enhanced sympathetic nervous system activity might influence optic nerve head perfusion and potentially increase the risk of NAION. Another notable finding was that the greatest risk of NAION appeared to be within the first year following the prescription of semaglutide, a temporal association that supports a potential drug-induced risk of NAION, the researchers pointed out
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In plain terms, that means they mimic the hormones your gut naturally releases after you eat a meal
Use caution in patients with a history of angioedema or anaphylaxis with a GLP-1 receptor agonist because it is unknown whether such patients will be predisposed to these reactions with MOUNJARO
While nausea and digestive changes are the most talked-about side effects, is leg pain a side effect of Ozempic is a question many people ask their providers as they navigate their treatment
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