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Kunze E, Chang-Claude J, Frentzel-Beyme R (1992) Life style and occupational risk factors for bladder cancer in Germany: a casecontrol study

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Cigarette smoke impairs endothelial function due to vagal input from the airway rather than a specific smoke constituent The ability of blood vessels to widen was examined in the rat study before and after exposure to smoke from four types of classic combustible cigarettes: conventional nicotine, reduced nicotine, conventional nicotine with added menthol, and reduced nicotine with added menthol