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The top 5 differential metabolites based on fold change in the ESC group were Allylestrenol, Mipafox, P-Tolyl Sulfate, 2-Hydroxypyridine and P-Cresol glucuronide

Inappropriate major histocompatibility complex class II expression by thyroid follicular cells in thyroid autoimmune disease and by pancreatic beta cells in type I diabetes

Common claims include gastrointestinal injuries, delayed gastric emptying, gallbladder disease, pancreatitis, or permanent vision loss

Sections from paraffin-embedded mouse skin were stained with hematoxylin and eosin

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Elevated blood glucose triggers hyperglucotoxicity, leading to aggravation of IR and deterioration of cell function, creating a vicious cycle that leads to further elevation of blood glucose to diabetic levels and even hyperglycemic crises