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In mice suffering from non - alcoholic fatty liver disease (NAFLD), liraglutide significantly elevated the abundance of Akkermansia , Romboutsia , and specific members of Bacteroidales, while reducing that of Klebsiella , Anaerotruncus , Bacteroides , and several taxa within the Lachnospiraceae and Ruminococcaceae families ( Firmicutes (e.g., Lachnospiraceae , Clostridiales ) and increased beneficial taxa like Verrucomicrobia and Oscillospiraceae (Madsen et al., 2019)
Semaglutide is a long-acting GLP-1 receptor agonist that mimics the action of endogenous GLP-1, an incretin hormone released from intestinal L-cells in response to food intake
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EGCGs ability to scavenge ROS while simultaneously boosting cellular antioxidant capacity makes it particularly effective in protecting mitochondria from oxidative damage [70]
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Deeper and wider knowledge concerning the mode of action of both PATs and APTs may help to develop therapeutic drugs that regulating the palmitoylation of specific target proteins
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