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Ferroptosis is a novel type of regulated cell death which is driven by iron-dependent lipid peroxidation and subsequent plasma membrane ruptures

Conversely high doses, and/or inadequate removal of ROS caused by several mechanisms, i.e., ionizing radiation, bioactivation of xenobiotics, inflammatory processes, increased cellular metabolism, activation of oxidases, and oxygenases, can be very dangerous, modifying susceptible molecules including DNA, lipids, and proteins

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