Many find adequate results at 10 mg or 12.5 mg with fewer side effects
People who might benefit the most from switching from semaglutide to tirzepatide include those who: Havent lost as much weight as they hoped to on semaglutide, or have run into a weight loss plateau Havent reached their target HbA1c levels on semaglutide, or are hoping for further reductions Have another health condition that only tirzepatide is FDA-approved to treat, such as obstructive sleep apnea If semaglutide hasnt been working well for you, it might be worth switching to tirzepatide
Unlike semaglutide, metformin also isnt likely to cause a loss of lean muscle tissue
As an endocrinologist who treats people with type 2, Im always excited about novel interventions that indicate significant positive outcomes
If you are more focused on cellular energy production, skin health, and NAD+ support, niacinamide may be more appropriate
However, the long-term safety and effects of intensive behavioral therapy and the effects of tirzepatide are a big concern for doctors, patients, and researchers