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& Porcaro, G

For individuals who tolerate tirzepatide well and do not require additional metabolic support, plain tirzepatide may be the best choice

The most commonly reported adverse effects of GLP-1-based therapies are gastrointestinal in nature

doi: 10.3390/diseases9040067 11 TamuraHTakasakiATanakaTTanabeMLeeLTamuraIet al

Exenatide treatment ameliorates these morphological alterations and inhibits the mitochondrial apoptotic pathway by suppressing cytochrome c release and favorably modulating the expression of pro-apoptotic (Bax, caspase-3) and anti-apoptotic (Bcl-2) proteins, thereby protecting RGC-5 cells from hyperglycemic injury [43]

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