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Divergent Molecular Mechanisms Underlying the Pleiotropic Functions of Macrophage Inhibitory Cytokine-1 in Cancer

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In cultured human brain microvascular endothelial cells, hyperglycemia and IL-1 treatment significantly increased transendothelial leakage and reduced the expression of junction proteins

Patients on Epithalon consistently report this as one of the earliest changes they notice, typically within the first two to three weeks of a protocol