Features of NHS-Activated Magnetic Beads: High capacity at least four times higher binding capacity than NHS-activated magnetic beads from other suppliers Easy to use immobilize in a simple one-step reaction with minimal hands-on time Safe no hazardous chemicals needed (e.g., sodium cyanoborohydride and cyanogen bromide) Ligand-compatible use to immobilize with nearly any primary amine-containing compound or affinity ligand Low non-specific binding the bead surface is pre-blocked and any nonreacted NHS-ester groups are fully quenched Protocol-compatible protein coupling to the beads and downstream applications can be performed manually or by automation (e.g., Thermo Scientific KingFisher Instruments) The activated magnetic beads contain N -hydroxy-succinimide (NHS) functional groups that react with primary amines forming stable amide linkages
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