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The most common Wegovy side effect is nausea, while diarrhea is the most common complaint with metformin

Although acute, short-term CORT elevation has anti-inflammatory effects, chronic stress disrupts negative feedback regulation, leading to increased levels of inflammatory cytokines such as IL-6 and TNF-, exacerbating esophageal mucosal damage and neural sensitivity

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Asano T, Katada T, Gilman AG, Ross EM (1984) Activation of the inhibitory GTP-binding protein of adenylate cyclase, Gi, by beta-adrenergic receptors in reconstituted phospholipid vesicles

Poor sleep is not considered a common or expected side effect of GLP1 agonists such as Wegovy or Mounjaro

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