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Advanced biomedical research

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Notably, in most countries PAC is freely sold as an OTC drug, raising the risk of unintentional abuse and increased adverse effects ( No answer can be given to the above open questions because PAC efficacy/adverse effects, unlike most of the drugs repositioned for COVID-19 therapy, have not yet been evaluated in controlled clinical trials or analyzed through retrospective analyses

Having sufficient levels of B12 has been linked to improved response to antidepressant medications, as several studies have shown

Behaviour 132 , 2147 (1995)