Several questions remain unanswered, including the association between survival benefit and specific type of organ system toxicities, toxicity grade, if the benefit is entirely due to immortal-time biases (ITBs), presence of patients confounding comorbidities like autoimmune diseases, and finally, immune heterogeneities
Endorsed by Leading Guidelines & Saudi MOH: The 2024 ADA/EASD Consensus Report firmly positions GLP-1 RAs like Ozempic as the first-line injectable after metformin, especially for patients with established ASCVD, HF, or obesity
These unregistered, unlicenced products present a potential significant safety risk to patients
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Dysplastic nevi are usually larger than normal nevi with macular or popular components and ill-defined borders (62)
Among the primary reasons reported for low adherence and persistence, the severity of adverse events was most common [37]