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Results Summary-level Mendelian randomisation of effect of smoking on bipolar disorder Across different methods of MR analyses, consistent evidence was found for a positive effect of smoking initiation on the odds of bipolar disorder (OR IVW = 1.46, 95% CI 1.281.66, P = 1.4 10 8 ) (Table 1, Fig

27,28 Including all medications, not just nicotine replacement medications, is a priority going forward as additional states consider implementing policies allowing pharmacists to prescribe cessation medications

Alcohol can break down the protective tissue covering the mucosa and increase cellular permeability to these molecules, in addition to accelerating the metabolism of tobacco tar into carcinogens

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The RCT conducted by Foshee et al