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Abstract Obstructive sleep apnea syndrome (OSAS) is closely associated with obesity and metabolic dysfunction

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Initially, both the GTP-bound GDH open and closed conformers were decomposed into rigid clusters and flexible regions using the program Floppy Inclusion and Rigid Substructure Topography (FIRST) and then RTA algorithm are applied to calculate if DOF propagate through protein structure as a result of rigidifying the GTP binding pocket

The honest clinical answer: it does not work like a GLP-1