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on the other hand, elevated levels of xanthine oxidase may lead to increased production of reactive oxygen species, which in turn increases lipid peroxidation reactions, aggravating the great damage to cells increasing cell turnover thus leading to increased purine catabolism and thus increased uric acid production 25

However, nicotine quantities in e-cigarettes vary tremendously

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An announcement is expected soon on whether the government will ban disposable vapes, after growing calls for action from leading paediatricians and councils

5c,d and Supplementary Figure S6c,d)

Comparative data on endotoxemia and NOX2 activation between adults and children exposed to either conventional or heated tobacco remain scarce