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In particular, increasing evidence highlights the pivotal role of innate immune activation in initiating and amplifying the adaptive immune response, particularly the activation of autoreactive CD8 + T cells, which are the ultimate effectors of melanocyte destruction

Human natural killer cells

That means waiting until your mixture has cooled to below 104F (40C) before stirring it in

doi: 10.1007/s10517-013-2029-0

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