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The peptide consists of 30 amino acids (the first 29 of GHRH plus a modification) with specific chemical alterations that resist enzymatic degradation and prolong receptor activation

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SAXENDA was evaluated for safety in 5 double-blind, placebo controlled trials that included 3,384 overweight or obese adult patients treated with SAXENDA for a treatment period up to 56 weeks (3 trials), 52 weeks (1 trial), and 32 weeks (1 trial) and one trial of 56 weeks in 125 pediatric patients with obesity aged 12 years and older [see Clinical Studies (14.1, 14.2)]

Label--Peptide Structures

Clinical studies examining this specific combination remain limited, so current evidence relies on mechanism-based reasoning and observational clinical reports rather than large randomized trials