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(64) showed that quercetin-loaded nanoparticles formulated with chitosan and gum arabic (QCG-NPs) exhibit significantly enhanced mucoadhesive properties in vitro , attributed to electrostatic interactions with the mucin layer

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Only strong stress inducers, such as hydrogen peroxide or UVB irradiation, activate NOX strongly enough for ascorbate to start inhibiting the enzyme [33,34]

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M1-like macrophages, characterized by elevated glycolysis, disrupted TCA cycle intermediates, enhanced ferritinophagy, and high ROS/NO production, naturally promote ferroptotic pressure