Li, C., Zhang, C., Wang, C., Zeng, R
It works through a unique mechanism involving the activation of two different types of receptors in the body: the glucagon-like peptide-1 (GLP-1) receptor and the glucose-dependent insulinotropic polypeptide (GIP) receptor
Mechanism of Action: Tirzepatide works by stimulating both GLP-1 and GIP receptors
The same year, Ward and colleagues published on an IgG Fc variant engineered for efficient engagement of FcRn to outcompete endogenous IgG in vivo, thus effectively increasing IgG catabolism
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