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The result suggests that sympathetic nervous system activation by GLP-1RA is due to direct activation of AP without bloodbrain barrier or indirect activation of NTS via vagal afferent nerves and AP

Kawai M, Imaizumi K, Ishikawa M, Shibata S, Shinozaki M, Shibata T, et al

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So, we talked about pleiotropic, which means does a bunch of things

Key areas of future research will include the signaling pathways and molecular mechanisms involved, endothelial repair, and interactions between endothelial cells and other cell types in sepsis (110)

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