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Excitotoxicity may occur when, for instance, extracellular glutamate accumulates due to impaired uptake by astrocytes or excessive synaptic release

[29] SIBO is known to be a potent cause of leaky gut

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Kerr D, Penfold S, Zouwail S, Thomas P, Begley J (2009) The influence of liberal alcohol consumption on glucose metabolism in patients with type 1 diabetes: a pilot study

The concern stems from its activation of the VEGFR2 pathway and FAK-paxillin signaling, which drive angiogenesis and are dysregulated in 50% of human cancers (ovarian cancer, melanoma, and colon adenocarcinoma)

doi: 10.3390/genes13050730