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A separate line of investigation, work by Pollard and colleagues, demonstrated that GHK-Cu could reverse detrimental changes in irradiated cultured human fibroblasts: cells exposed to significant radiation and then treated with GHK-Cu at very low concentrations displayed a growth pattern and growth-factor secretion profile comparable to non-irradiated control cells, including increased secretion of bFGF and VEGF

The developing fetus and newborn are acutely sensitive to epigenetic disruption, particularly in the methylation cycle

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Coffee B, Keith K, Albizua I, Malone T, Mowrey J, Sherman SL, et al