If clinical suspicion exists based on history or examination findings, appropriate evaluationpotentially including thyroid ultrasound, serum calcitonin, or genetic testing for RET mutationsshould be completed before starting therapy
Animal studies have also shown an increased risk of thyroid C-cell tumors with these medications, but this risk hasnt been confirmed in people
In March, Novo Nordisk announced that patients regained two-thirds of their weight one year after stopping semaglutide treatment
They may recommend temporarily holding semaglutide, adjusting the dose, or scheduling an in-person evaluation
Semaglutide dosing follows what's known as a dose escalation scheme
Dosing and Administration Differences Brand-name semaglutide products come in prefilled injection pens with precise dosing mechanisms