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Disclosure Statement This article is published as part of a journal supplement wholly funded by Laboratoires dermatologiques Avne

Chronic studies in cynomolgus monkeys revealed no adverse events at a dose of 20 mg/kg per day [88], and high-dose supplementation in rhesus monkeys caused no ocular toxicity [89]

From what the study suggests, AOD 9604 may assist in the transition of these precursor cells into a more mature form

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This study demonstrated that cultured hepatocytes treated either with a precursor of GSH, such as L-cysteine or N-acetylcysteine, or with its soluble ethyl ester form, boosts the levels of cellular GSH, which upregulates CYP27A1, CYP27B1, and VDR but downregulates CYP24A1