Morgan, R
The purpose of these specification markers is to help laboratories treat the reagent as a stable reference point across experiments, improving comparability across runs and across operators
The peptide also induces the expression of vascular endothelial growth factor (VEGF) and angiopoietin-1, promoting angiogenesis in injured tissues
But its a bit more complex than that
The reasons: Receptor sensitivity: While GHK-Cu doesn't appear to cause receptor downregulation the way some peptides do, cycling is a general precaution to maintain responsiveness and avoid adaptations that might blunt benefits
J Clin Invest (2000) 106:15119 10.1172/JCI10226 [DOI] [PMC free article] [PubMed] [Google Scholar] 153.Morishita R, Nakamura S, Hayashi S, Taniyama Y, Moriguchi A, Nagano T, et al